ICMR surveillance data from January 2017 to December 2017: Among the diarrheal pathogens, Aeromonas spp is one of the most isolated species among diarrheal pathogens. Aeromonas spp showed moderate resistance to all tested antibiotics. Resistance to carbapenems especially imipenem, was higher compared to other classes of antibiotics. Most Aeromonas strains are generally susceptible to trimethoprim-sulfamethoxazole (TMP-SMX), fluoroquinolones, second and third generation cephalosporins, aminoglycosides, carbapenems, chloramphenicol, and tetracyclines. Shigella spp is the second common diarrheal pathogen and the isolates demonstrated increased resistance to nalidixic acid and trimethoprim sulfamethoxazole (89.9%). Tetracycline still appears to be effective for V cholerae.